12 個首次披露的小分子在新藥研究領域的前景匯總

在落幕的 ACS Spring 2025 (美國化學會春季年會) 上，多個創新藥物首次披露，涵蓋了腫瘤、心血管、神經系統疾病等多個領域。

這些小分子藥物代表了當下最前沿的藥物化學設計趨勢。這些首次亮相的“新星”是否有望成為下一代重磅新藥？跟隨小 M 一起來看看它們的背景信息。

 
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小結

這 12 個首次亮相的小分子藥物，不僅展示了目前藥物研發的多樣化方向 (從傳統抑制劑到蛋白降解劑、共價靶向劑、大環肽等)，也反映出精準醫療背景下對突變蛋白、腫瘤微環境、腦部靶點等復雜機制的深入探索。部分分子已經進入臨床階段，值得持續關注。
 

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